Evidence-Based Supplementation

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Clinical Knowledge Hub

The Science of Healthy Living

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Hashimoto's Thyroiditis: The Supplement Protocol Your Endocrinologist Should Know
Condition Guide

Hashimoto's Thyroiditis: The Supplement Protocol Your Endocrinologist Should Know

Selenium 200 mcg reduces TPO antibodies. High-dose iodine makes Hashimoto's worse. Here's the evidence-based supplement protocol — and the common mistakes that harm patients.

10 min read
Read
Sleep Optimization: A Pharmacologist's Guide to Sleep Supplements
Deep Dive

Sleep Optimization: A Pharmacologist's Guide to Sleep Supplements

Melatonin at 0.5 mg works better than 10 mg. Glycine lowers core body temperature. Here's what a pharmacologist actually recommends for sleep — and the drug interactions you need to know.

9 min read
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The Science of Stress Supplements: Adaptogens That Actually Work
Evidence Review

The Science of Stress Supplements: Adaptogens That Actually Work

Ashwagandha cut cortisol by 30% in RCTs. L-theanine works in 30 minutes. Here's what the clinical trials show about adaptogens — and when supplements aren't enough.

5 min read
Read

How it works

A systematic, evidence-based approach

Four steps from your health profile to a personalized protocol. Not guesswork.

  1. 1

    Health Assessment

    Answer questions about your health, medications, lifestyle, and goals. Add lab results or genetic data for even better results.

  2. 2

    Evidence Matching

    Our algorithm searches a curated knowledge base of supplement-condition mappings, each rated by evidence strength.

  3. 3

    Safety Screening

    Every recommendation is cross-checked against your medications for interactions. Unsafe combinations are automatically blocked.

  4. 4

    Your Plan

    Receive a personalized plan with 5-8 supplements, optimal doses, timing schedule, and clear explanations for each one.

Built on peer-reviewed research
Drug interaction safety checks
Clinician-Designed & Evidence-Based
A calm morning routine with supplements and linen

Built into your day

“A supplement plan shouldn’t feel like a prescription. It should feel like a morning ritual.”

What makes us different

Clinically-driven, not marketing-driven

Overhead flatlay of supplement bottles

Drug Interaction Checks

Every supplement, screened against your medications

Critical interactions are blocked automatically. Moderate ones are flagged with clear warnings. We check against warfarin, metformin, SSRIs, statins, thyroid meds, and more.

Learn more about our safety checks
Macro close-up of vitamins and minerals

Evidence Ratings

Strong, moderate, emerging — you decide

Every recommendation shows its evidence level — Strong (multiple RCTs), Moderate (some studies), Emerging (preliminary research), or Traditional (historical use) — so you know exactly what the science says.

See our methodology
Laboratory setup with microscope and supplement bottles

Deterministic Algorithm

Structured clinical rules, not a chatbot

NutriGenius uses a curated knowledge base of supplement-condition mappings, drug interactions, dosage limits, and safety rules. Not a language model making guesses — a structured engine producing consistent, evidence-based recommendations.

Read about our algorithm

Additional features

Lab-Informed Dosing

Biomarker-calibrated recommendations from your blood work.

Visual Weekly Schedule

Morning, midday, evening — timing optimized for absorption.

Genetic Personalization

MTHFR, COMT, VDR variants inform supplement form selection.

Clinician-Designed Protocols

Medically reviewed rules from practicing clinicians.

Member Experiences

What our members are saying

Real stories from people using NutriGenius to navigate conditions, diets, and life stages with personalized, evidence-based protocols.

The interaction checks flagged a supplement that would've clashed with my levothyroxine. My GP confirmed NutriGenius caught something I'd have missed on my own.

Sarah M.

Managing hypothyroidism

As a vegan, I was always guessing at B12 and omega-3. The algorithm picked the exact forms and doses I needed — and pointed me to algae DHA I didn't know existed.

David K.

Plant-based diet

I uploaded my recent bloodwork and got a protocol tuned to my actual ferritin and vitamin D numbers. It felt like a real consultation, not a generic quiz.

Priya R.

Perimenopause support

Between training cycles my recovery stalled. The magnesium form and creatine timing NutriGenius suggested shifted things within three weeks.

Marcus T.

High-performance athlete

I was overwhelmed by conflicting advice online. The personalized protocol cut through the noise and gave me a simple, safe routine I actually stick to.

Elena V.

First-time supplement user

The evidence ratings on every recommendation helped me explain my stack to my cardiologist. She appreciated that nothing was pseudoscience — all cited trials.

James O.

Post-cardiac rehab

Safety First

Your safety is non-negotiable

Medically reviewed by Dr. Esra Ata, MD — a physician certified in Functional Medicine and GAPS Protocol. Clinical architecture by a Pharmaceutical Clinical Development Expert. Every recommendation passes through multiple safety layers before it reaches you.

Supplements with critical drug interactions are automatically blocked
Doses never exceed established Upper Tolerable Intake Levels
Pregnancy and breastfeeding restrictions are strictly enforced
All recommendations include evidence ratings and source transparency
This platform supplements — never replaces — professional medical advice
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